Following the signature of the first MLS players' union contract, the MLS Superdraft was limited to four rounds. As a result, the Supplemental Draft was re-incarnated to hold the additional rounds. The 2005 MLS supplemental draft, held on February 4, 2005, was the first re-incarnation of the MLS supplemental draft. The four-round event followed January's 2005 MLS SuperDraft, as teams filled out their developmental rosters. Expansion clubs Real Salt Lake and Chivas USA received the first picks in each round.
The most notable draft picks include fourth round draft picks Chris Wondolowski, who is one of the top career goalscorers in Major League Soccer with over 140 career MLS goals, and Jeff Larentowicz, who has played more than 380 matches in more than 10 seasons in Major League Soccer.
| * | Denotes player who has been selected for an MLS Best XI team |