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| Administrator(s) | African Cricket Association |
|---|---|
| Cricket format | 50 overs per side |
| Tournament format(s) | round robin with playoffs |
| Host(s) |  South Africa |
| Champions |  Mozambique |
| Participants | 8 |
| Matches | 20 |
| Most runs | Kaleem Shah 313 |
| Most wickets |  Peter Ananya 14 |
The 2006 ICC World Cricket League Africa Region Division Three was a cricket tournament in South Africa, taking place between 23 April and 28 April 2006. It gave eight African Associate and Affiliate members of the International Cricket Council experience of international one-day cricket and formed part of the global World Cricket League structure.
The top team, Mozambique was promoted to Division 2.