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| Date | April 28–29, 2006 | ||||||||||||||||||
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| Venue | Xavier University Gym, Cagayan de Oro | ||||||||||||||||||
| MVP | Asi Taulava (Talk 'N Text Phone Pals) | ||||||||||||||||||
| Network | Associated Broadcasting Company (ABC) | ||||||||||||||||||
The 2006 Hope-PBA All-Star Weekend was the annual all-star weekend of the Philippine Basketball Association (PBA)'s 2005–06 PBA season. This was the second all-star weekend held in the season, due to the league adjusting its season calendar.