| Tournament details | |
|---|---|
| Country | United States |
| Final positions | |
| Champions | Chicago Fire (4th title) |
| Runner-up | Los Angeles Galaxy |
| Tournament statistics | |
| Top goal scorer(s) | Tomas Boltnar Andy Herron Ben Hollingsworth Randi Patterson (4 goals each) |
The 2006 Lamar Hunt U.S. Open Cup ran from June through September, open to all soccer teams in the United States.
The Chicago Fire won 3–1 over defending-champion Los Angeles Galaxy in the final at Toyota Park in Bridgeview, Illinois. It was the Fire's fourth Open Cup title in nine years.
The early rounds were most notable for the surprising run of amateur side Dallas Roma F.C. of the North Texas Premier Soccer Association. Roma barely survived the first round in a penalty shootout win over PDL side Laredo Heat before upsetting Miami FC of the USL First Division 1–0 in the second round. Roma's biggest upset came in the third round with another shootout win, this time over CD Chivas USA.
The latter rounds of the tournament were dominated by MLS teams and both semifinals were matchups between conference rivals. The Galaxy, who had ended Roma's Cinderella run, beat Houston Dynamo in one semifinal, while Chicago beat league leader D.C. United in the other semifinal. In the championship game played at first-year Toyota Park, the host side scored two early goals en route to their 3–1 win.