The 2006 United States Senate election in Nevada was held on November 7, 2006. Incumbent Republican John Ensign defeated Democratic nominee Jack Carter to win re-election to a second term. This election was the only Senate election in Nevada where the incumbent Republican Senator was re-elected or won re-election since 1980 and the only Senate election in Nevada for this seat where the incumbent Republican Senator was re-elected or won re-election since 1952.