| 2016 Currie Cup Premier Division | |
|---|---|
 The Currie Cup in 2012 | |
| Countries | South Africa |
| Date | 5 August – 22 October 2016 |
| Champions | Free State Cheetahs (5th title) |
| Runners-up | Blue Bulls |
| Relegated | Boland Cavaliers Eastern Province Kings |
| Matches played | 39 |
| Tries scored | 321 (average 8.2 per match) |
| Top point scorer | Tian Schoeman (146) |
| Top try scorer | Frank Herne, Huw Jones, Howard Mnisi, Kwagga Smith and Jamba Ulengo (7) |
The 2016 Currie Cup Premier Division was the top tier of the second stage of the 2016 Currie Cup, the 78th edition of this annual South African rugby union competition organised by the South African Rugby Union. It was played between 5 August and 22 October 2016 and featured nine teams that qualified through the 2016 Currie Cup qualification competition.
The competition was won by the Free State Cheetahs for the fifth time in their history; they beat the Blue Bulls 36–16 in the final played on 22 October 2016.
The competition was reduced to seven teams for 2017, resulting in the Boland Cavaliers and Eastern Province Kings being relegated to the 2017 Currie Cup First Division.