| Season | 2016 |
|---|---|
| Champions | Ayutthaya Warrior |
| Relegated | Uthai Thani Forest |
| Matches played | 110 |
| Goals scored | 233 (2.12 per match) |
| Top goalscorer | Ousmanou Mohamadou (14 Goals) |
| Biggest home win | Singburi 4–1 PTU (4 June 2016) |
| Biggest away win | Chaiyaphum 0–3 Saraburi TRU (14 May 2016) |
| Highest scoring | Ayutthaya Warrior 4–3 Uthai Thani (2 July 2016) |
| Longest winning run | 9 Matches Ayutthaya |
| Longest unbeaten run | 10 Matches Ayutthaya |
| Longest losing run | 5 Matches Chaiyaphum |
| Highest attendance | 1,739 Ayutthaya Warrior 2–0 Ayutthaya (30 July 2016) |
| Lowest attendance | 40 Uthai Thani 1–3 Ayutthaya (5 June 2016) |
| Total attendance | 50,131 |
| Average attendance | 477 |
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2016 Regional League Division 2 Central Region is the 1st season of the League competition since its establishment in 2016. It is in the third tier of the Thai football league system. The league winners and runners up will qualify for the 2016 Regional League Division 2 champions league round. This zone is broken from 2015 Thai Division 2 League Central & Eastern Region and 2015 Thai Division 2 League Central & Western Region