| Dates | 20 May 2016 – 20 August 2016 |
|---|---|
| Administrator(s) | England and Wales Cricket Board |
| Cricket format | Twenty20 |
| Tournament format(s) | Group stage and knockout |
| Champions | Northamptonshire (2nd title) |
| Participants | 18 |
| Matches | 133 |
| Most runs | Michael Klinger (548) |
| Most wickets | Benny Howell (24) |
| Official website | NatWest T20 Blast |
The 2016 NatWest T20 Blast was the fourteenth edition of the T20 Blast, the domestic T20 competition run by the ECB. The league consisted of the 18 first-class county teams divided into two divisions of nine teams each with fixtures played between May and August. The final took place at Edgbaston Cricket Ground in Birmingham on 20 August 2016.