The 2019 Central League Climax Series (CLCS) was a postseason playoff consisting of two consecutive series that determined which of the three teams who finished in the top three during the 2019 regular season would represent the Central League in the Japan Series. The First Stage was a best-of-three series played between the second-place hosts Yokohama DeNA BayStars and the third-place Hanshin Tigers. The series was played between October 5 to 7. The Tigers defeated the Baystars 2–1 and advanced to the Final Stage to face the pennant-winning Yomiuri Giants.
The Final Stage was a best-of-six series hosted by the Giants. Having won the regular season, Yomiuri was awarded a one-win advantage over the Tigers. The series was played between October 9 to 13. Yomiuri defeated Hanshin 4–1 in four games to advance to the 2019 Japan Series, where they competed against the 2019 Pacific League Climax Series winner, the Fukuoka SoftBank Hawks.