| 2021 Cary Challenger | |
|---|---|
| Date | 19–25 July |
| Edition | 7th |
| Surface | Hard |
| Location | Cary, North Carolina, United States |
| Champions | |
| Singles | |
 Mitchell Krueger | |
| Doubles | |
| Christian Harrison / Dennis Novikov | |
The 2021 Cary Challenger was a professional tennis tournament being played on hard courts. It was the 7th edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Cary, North Carolina, United States between 19 and 25 July 2021.