The 2021 Grand Prix of Long Beach (formally known as the Acura Grand Prix of Long Beach) was a sports car race sanctioned by the International Motor Sports Association (IMSA). The race was held at Long Beach street circuit in Long Beach, California on September 25, 2021. It was the tenth round of the 2021 IMSA SportsCar Championship, and seventh the round of 2021 WeatherTech Sprint Cup.