| Tournament details | |
|---|---|
| Dates | 31 October–1 December 2021 |
| Teams | 26 |
| Defending champions | Persiku Kudus |
| Final positions | |
| Champions | Persipa Pati (1st title) |
| Runner-up | Persebi Boyolali |
| Third place | Persak Kebumen |
| Fourth place | PSIP Pemalang |
The 2021 Liga 3 Central Java (also known as Liga 3 MS Glow For Men PSSI Jawa Tengah for sponsorship reason[1]) will be the sixth season of Liga 3 Central Java as a qualifying round for the national round of the 2021–22 Liga 3.
Persiku Kudus were the defending champion.