| 2021 season | ||||
|---|---|---|---|---|
| President | Andrés Rueda | |||
| Coach | Ariel Holan (until 25 April) Marcelo Fernandes (caretaker, 26 April 2021 – 6 May 2021) Fernando Diniz (from 7 May 2021 – until 5 September 2021) Fábio Carille (since 8 September 2021) | |||
| Stadium | Vila Belmiro | |||
| Campeonato Brasileiro | 10th | |||
| Campeonato Paulista | Group stage | |||
| Copa do Brasil | Quarter-finals | |||
| Copa Libertadores | Group stage | |||
| Copa Sudamericana | Quarter-finals | |||
| Top goalscorer | League: Marinho (6) All: Marinho (9) | |||
|
| ||||
The 2021 season was Santos FC's 109th season in existence and the club's sixty-second consecutive season in the top flight of Brazilian football. As well as the Campeonato Brasileiro, the club competed in the Copa do Brasil, Campeonato Paulista and the Copa Libertadores.