| Tournament details | |
|---|---|
| Country | Tajikistan |
| Dates | 24 May 2021 – 9 December 2021 |
| Teams | 22 |
| Defending champions | Ravshan |
| Final positions | |
| Champions | Khujand |
| Runner-up | Istiklol |
| Tournament statistics | |
| Matches played | 23 |
| Goals scored | 90 (3.91 per match) |
| Top goal scorer(s) | Akbar Bobomurodov (4) |
All statistics correct as of 9 December 2021. | |
The 2021 Tajikistan Cup was the 30th edition of the Tajikistan Cup, the knockout football tournament of Tajikistan, with the winner of the cup qualifying for the 2022 AFC Cup.