The 2022 1000 Miles of Sebring was an endurance sportscar racing event held on the 18 March 2022, as the opening round of the 2022 FIA World Endurance Championship. This was the second running of the race, a 268-lap event or 8 hours (whichever comes first), and the first time the event had been held since the 2019 1000 Miles of Sebring, after due to the 2020 and 2021 races being cancelled by the COVID-19 pandemic.