| 2022 BOSS Open | |
|---|---|
| Date | 6–12 June |
| Edition | 44th |
| Category | ATP Tour 250 |
| Draw | 28S / 16D |
| Prize money | € 769,645 |
| Surface | Grass |
| Location | Stuttgart, Germany |
| Venue | Tennis Club Weissenhof |
| Champions | |
| Singles | |
 Matteo Berrettini | |
| Doubles | |
 Hubert Hurkacz /  Mate Pavić | |
The 2022 BOSS Open was a men's tennis tournament played on outdoor grass courts. It was the 44th edition of the Stuttgart Open, and part of the ATP Tour 250 series of the 2022 ATP Tour. It was held at the Tennis Club Weissenhof in Stuttgart, Germany, from 6 June until 12 June 2022. Second-seed Matteo Berrettini won the singles title.