| 2022 Cary Challenger | |
|---|---|
| Date | 12–18 September |
| Edition | 9th |
| Surface | Hard |
| Location | Cary, North Carolina, United States |
| Champions | |
| Singles | |
 Michael Mmoh | |
| Doubles | |
| Nathaniel Lammons / Jackson Withrow | |
The 2022 Cary Challenger was a professional tennis tournament being played on hard courts. It was the 9th edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Cary, North Carolina, United States between 12 and 18 September 2022.