| 2022 Columbus Challenger | |
|---|---|
| Date | January 24–30 |
| Edition | 11th |
| Draw | 32S / 16D |
| Prize money | $52,080 |
| Surface | Hard (indoor) |
| Location | Columbus, United States |
| Venue | Ohio State Varsity Tennis Center |
| Champions | |
| Singles | |
 Yoshihito Nishioka | |
| Doubles | |
 Tennys Sandgren /  Mikael Torpegaard | |
The 2022 Columbus Challenger was a professional tennis tournament played on indoor hard courts. It was the eleventh edition of the men's tournament which was part of the 2022 ATP Challenger Tour. It took place in Columbus, United States between January 24 and 30 2022.