| 2022 San Benedetto Tennis Cup | |
|---|---|
| Date | 25 – 31 July |
| Edition | 16th |
| Category | ATP Challenger Tour |
| Surface | Clay |
| Location | San Benedetto del Tronto, Italy |
| Champions | |
| Singles | |
 Raúl Brancaccio | |
| Doubles | |
 Vladyslav Manafov / Oleg Prihodko | |
The 2022 San Benedetto Tennis Cup was a professional tennis tournaments played on clay courts. It was the 16th edition of the tournament which was part of the 2022 ATP Challenger Tour. The event took place in San Benedetto del Tronto, Italy, from 25 to 31 July 2022.