| 2023 Knoxville Challenger | |
|---|---|
| Date | 6–12 November |
| Edition | 19th |
| Surface | Hard (Indoor) |
| Location | Knoxville, United States |
| Champions | |
| Singles | |
 Alex Michelsen | |
| Doubles | |
Cannon Kingsley /  Luis David Martínez | |
The 2023 Knoxville Challenger was a professional tennis tournament played on indoor hard courts. It was the 19th edition of the tournament which was part of the 2023 ATP Challenger Tour. It took place in Knoxville, United States between 6 and 12 November 2023.