| 2024 Knoxville Challenger | |
|---|---|
| Date | 4–10 November |
| Edition | 20th |
| Surface | Hard (Indoor) |
| Location | Knoxville, United States |
| Champions | |
| Singles | |
 Christopher Eubanks | |
| Doubles | |
 Patrick Harper /  Johannus Monday | |
The 2024 Knoxville Challenger was a professional tennis tournament played on indoor hard courts. It was the 20th edition of the tournament which was part of the 2024 ATP Challenger Tour. It took place in Knoxville, United States between 4 and 10 November 2024.