| 3-oxoacyl-[acyl-carrier-protein] reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
_reductase&sq=&lang=&file=File:3rsh.jpg) 3-oxoacyl-[acyl-carrier-protein] reductase homotetramer, Vibrio cholerae | |||||||||
| Identifiers | |||||||||
| EC no. | 1.1.1.100 | ||||||||
| CAS no. | 37250-34-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) is an enzyme that catalyzes the chemical reaction
- 3-oxoacyl-[acyl-carrier-protein](ACP) + NADPH + H+ (3R)-3-hydroxyacyl-[acyl-carrier-protein](ACP) + NADP+
_reductase&sq=&lang=&file=File:3-oxoacyl-ACP_reductase_reaction.svg)
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group as hydride donor with NAD+ or NADP+ as hydride acceptor. The systematic name of this enzyme class is (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NADP+ oxidoreductase. Other names in common use include beta-ketoacyl-[acyl-carrier protein](ACP) reductase, beta-ketoacyl acyl carrier protein (ACP) reductase, beta-ketoacyl reductase, beta-ketoacyl thioester reductase, beta-ketoacyl-ACP reductase, beta-ketoacyl-acyl carrier protein reductase, 3-ketoacyl acyl carrier protein reductase, 3-ketoacyl ACP reductase, NADPH-specific 3-oxoacyl-[acylcarrier protein]reductase, and 3-oxoacyl-[ACP]reductase. This enzyme participates in fatty acid biosynthesis and polyunsaturated fatty acid biosynthesis.