3T3 cells are several cell lines of mouse embryonic fibroblasts. The original 3T3 cell line (3T3-Swiss albino) was established in 1962 by two scientists then at the Department of Pathology in the New York University School of Medicine, George Todaro and Howard Green. Todaro and Green originally obtained their 3T3 cells from Swiss albino mouse embryo tissue.[1] Later, as a principal investigator position at the National Cancer Institute in Bethesda, Maryland, Todaro repeated the isolation procedure from the NIH Swiss mouse embryo with his students and established NIH-3T3 cell line.[2]
- ^ Todaro, GJ; Green, H (1963). "Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines". J. Cell Biol. 17 (2): 299–313. doi:10.1083/jcb.17.2.299. PMC 2106200. PMID 13985244.
- ^ "Generating the 3T3 cell line, the oncogene hypothesis and horses". www.asbmb.org. Retrieved 2020-07-28.