The 45th General Assembly of Prince Edward Island was in session from February 15, 1944, to October 27, 1947. The Liberal Party led by John Walter Jones formed the government.
Thomas R. Cullen was elected speaker.
There were four sessions of the 45th General Assembly:
| Session | Start | End |
|---|---|---|
| 1st | February 15, 1944 | March 17, 1944 |
| 2nd | March 13, 1945 | April 19, 1945 |
| 3rd | February 26, 1946 | March 30, 1946 |
| 4th | March 18, 1947 | April 25, 1947 |