5-HT1D receptor

HTR1D
Identifiers
Aliases	HTR1D, 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4, 5-HT1D receptor, 5-hydroxytryptamine receptor 1D
External IDs	OMIM: 182133; MGI: 96276; HomoloGene: 20240; GeneCards: HTR1D; OMA:HTR1D - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	23,217,502 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	136,171,709 bp
RNA expression pattern
	Top expressed in
	testicle; ; nucleus accumbens; ; putamen; ; duodenum; ; caudate nucleus; ; gallbladder; ; gonad; ; ganglionic eminence; ; stromal cell of endometrium; ; prefrontal cortex;
	Top expressed in
	paraventricular nucleus of thalamus; ; lumbar spinal ganglion; ; lateral habenular nucleus; ; ventral nuclear group; ; lateral preoptic nucleus; ; multiform layer of neocortex; ; medial habenular nucleus; ; ventral nucleus of lateral geniculate body; ; embryo; ; nucleus of lateral olfactory tract;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; G protein-coupled serotonin receptor activity; neurotransmitter receptor activity; serotonin binding;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane; dendrite;
Biological process	intestine smooth muscle contraction; regulation of locomotion; smooth muscle contraction; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; regulation of behavior; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; response to toxic substance; vasoconstriction; signal transduction; chemical synaptic transmission; G protein-coupled serotonin receptor signaling pathway; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	3352
	15552
	ENSG00000179546
	ENSMUSG00000070687
	P28221
	Q61224
	NM_000864
	NM_001285482; NM_001285483; NM_001285484; NM_008309
	NP_000855
	NP_001272411; NP_001272412; NP_001272413; NP_032335
	Wikidata
View/Edit Human	View/Edit Mouse

5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it.^[5] 5-HT_1D acts on the central nervous system, and affects locomotion and anxiety. It also induces vasoconstriction in the brain.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000179546 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000070687 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: HTR1D 5-hydroxytryptamine (serotonin) receptor 1D".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000179546 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000070687 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: HTR1D 5-hydroxytryptamine (serotonin) receptor 1D".

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