October 16 – Wu Zetian ascends to the throne of the Tang dynasty, and proclaims herself ruler of the Chinese Empire as "Holy and Divine Emperor". She becomes the first and only female "emperor" in 5,000 years of Chinese history. Wu Zetian changes the dynasty's name to the Zhou dynasty, and begins to murder throne pretendants and ministers who try to oppose her. During her reign she elevates the status of Buddhism above Taoism.
King Ine of Wessex establishes his West Saxon "Law of Codes", to regain authority in his kingdom.[5] He consolidates Wessex's territory in the western peninsula (approximate date).
Empress Jitō abdicates the throne in favor of the 14-year-old Monmu (grandson of late emperor Tenmu). During her 11-year reign she has established the foundations of law in Japan.
Autumn–winter – The Byzantine general Heraclius, brother of Tiberios III, crosses the mountain passes of the Taurus Mountains into Cilicia with an army. He launches a campaign in Syria, defeats an Arab force from Antioch, and raids as far as Samosata (modern Turkey).[11][12]
Outbreak of bubonic plague in Constantinople, Syria and Mesopotamia: Theophanes the Confessor reports that the plague lasted four months and describes a large number of deaths in Constantinople. Emperor Leontios orders the destruction of a market in the Neorion cargo port of Constantinople, where animals are sold and which is considered to be the source of infected animals brought from Syria. The Arab army is forced to suspend its military operations. According to Syrian sources, the plague in Syria lasted another two years.
Berber forces led by Queen Kahina ("The Diviner") are crushed by Arab invaders at Aures (Algeria). She has rallied the Berbers since the collapse of Byzantine power (see 647).