A16

A16, A 16, A.16 or A-16 may refer to:

• A16 road, in several countries
• ATC code A16, Other alimentary tract and metabolism products, a subgroup of the Anatomical Therapeutic Chemical Classification System
• British NVC community A16 (Callitriche stagnalis community), a British Isles plant community

It may also refer to:

• A16, a restaurant in the San Francisco Bay Area
• Subfamily A16, a rhodopsin-like receptors subfamily
• One of the Encyclopaedia of Chess Openings codes for the English Opening in chess
• Washington A16, 2000 Protests in Washington, D.C. against the International Monetary Fund and the World Bank on April 16 of 2000 and 2005, both known as "A16"