ACO2

ACO2
Identifiers
Aliases	ACO2, ACONM, ICRD, OCA8, HEL-S-284, OPA9, aconitase 2
External IDs	OMIM: 100850; MGI: 87880; HomoloGene: 856; GeneCards: ACO2; OMA:ACO2 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	41,529,273 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	81,799,334 bp
RNA expression pattern
	Top expressed in
	right ventricle; ; apex of heart; ; myocardium of left ventricle; ; gastrocnemius muscle; ; muscle of thigh; ; right auricle; ; jejunal mucosa; ; cardiac muscle tissue of right atrium; ; Skeletal muscle tissue of biceps brachii; ; vastus lateralis muscle;
	Top expressed in
	cardiac muscle tissue of left ventricle; ; right ventricle; ; extensor digitorum longus muscle; ; plantaris muscle; ; soleus muscle; ; extraocular muscle; ; digastric muscle; ; gastrocnemius muscle; ; interventricular septum; ; tibialis anterior muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	iron ion binding; 4 iron, 4 sulfur cluster binding; iron-sulfur cluster binding; 3 iron, 4 sulfur cluster binding; metal ion binding; lyase activity; aconitate hydratase activity;
Cellular component	myelin sheath; mitochondrial matrix; mitochondrion; cytosol;
Biological process	citrate metabolic process; metabolism; tricarboxylic acid cycle; generation of precursor metabolites and energy; isocitrate metabolic process; liver development; response to isolation stress;
	Sources:Amigo / QuickGO
Orthologs
	50
	11429
	ENSG00000100412
	ENSMUSG00000022477
	Q99798
	Q99KI0
	NM_001098
	NM_080633
	NP_001089
	NP_542364
	Wikidata
View/Edit Human	View/Edit Mouse

Aconitase 2, mitochondrial is a protein that in humans is encoded by the ACO2 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000100412 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022477 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Aconitase 2, mitochondrial".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000100412 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022477 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Aconitase 2, mitochondrial".

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