ADB-5'Br-PINACA

ADB-5'Br-PINACA
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class B
Identifiers
  • N-(1-Amino-3,3-dimethyl-1-oxo-2-butanyl)-1-pentyl-1H-5-bromoindazole-3-carboxamide
PubChem CID
ChemSpider
Chemical and physical data
FormulaC19H27BrN4O2
Molar mass423.355 g·mol−1
3D model (JSmol)
  • NC(=O)[C@@H](NC(=O)c1nn(CCCCC)c2ccc(Br)cc21)C(C)(C)C
  • InChI=1S/C19H27BrN4O2/c1-5-6-7-10-24-14-9-8-12(20)11-13(14)15(23-24)18(26)22-16(17(21)25)19(2,3)4/h8-9,11,16H,5-7,10H2,1-4H3,(H2,21,25)(H,22,26)/t16-/m1/s1
  • Key:OUVRBTCXLMBRLT-MRXNPFEDSA-N

ADB-5'Br-PINACA (5'-Br-ADB-PINACA) is an indazole-3-carboxamide based synthetic cannabinoid receptor agonist that has been sold as a designer drug. It was first identified in Abu Dhabi in September 2022[1] but has subsequently been found in the US and Europe.[2] While formal pharmacology studies have not yet been carried out, ADB-5'Br-PINACA is believed to be a highly potent synthetic cannabinoid with similar potency to compounds such as MDMB-FUBINACA and 5F-ADB, which have been responsible for numerous fatal and non-fatal drug overdoses, consistent with previously reported compounds from the patent literature showing bromination of the indazole ring at the 5-, 6-, or 7- positions to increase potency over the unsubstituted analogues.[3] ADB-5'Br-PINACA is the 5'-bromo analog of ADB-PINACA.

  1. ^ "The ADJD's Centre of Forensic and Digital Sciences Discovers a New Synthetic Cannabinoid Substance". Emirates 24/7. 15 May 2023.
  2. ^ "ADB-5'Br-PINACA Monograph". The Center For Forensic Science Research & Education. April 2023.
  3. ^ WO 2009106982, Buchler IP, Hayes MJ, Hedge SG, Hockerman SL, Jones DE, Kortum SW, Rico JG, Tenbrink RE, Wu KK, "Indazole Derivatives", published 3 September 2009, assigned to Pfizer Inc.