ADCY10

ADCY10
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4CLK, 4CLL, 4CLP, 4CLS, 4CLT, 4CLU, 4CLW, 4CLY, 4CLZ, 4CM0, 4CM2, 4OYA, 4OYB, 4OYI, 4OYM, 4OYO, 4OYP, 4OYW, 4OYX, 4OYZ, 4OZ2, 4OZ3, 4UST, 4USU, 4USV, 4USW, 5D0R
Identifiers
Aliases	ADCY10, HCA2, SAC, SACI, Sacy, hsAC, HEL-S-7a, adenylate cyclase 10 (soluble), adenylate cyclase 10, soluble, adenylate cyclase 10
External IDs	OMIM: 605205; MGI: 2660854; HomoloGene: 10188; GeneCards: ADCY10; OMA:ADCY10 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	167,914,215 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	165,404,343 bp
RNA expression pattern
	Top expressed in
	sperm; ; left testis; ; right testis; ; buccal mucosa cell; ; right lobe of liver; ; testicle; ; gonad; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; mucosa of transverse colon;
	Top expressed in
	spermatid; ; spermatocyte; ; seminiferous tubule; ; embryo; ; embryo; ; granulocyte; ; morula; ; blastocyst; ; zygote; ; lumbar subsegment of spinal cord;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; manganese ion binding; metal ion binding; lyase activity; adenylate cyclase activity; phosphorus-oxygen lyase activity; bicarbonate binding; ATP binding; magnesium ion binding; ATPase binding;
Cellular component	cytoplasm; cytosol; cell projection; membrane; microtubule cytoskeleton; growth cone; basal part of cell; plasma membrane; apical part of cell; cilium; axon; neuronal cell body; dendrite; mitochondrion; perinuclear region of cytoplasm; motile cilium; cytoskeleton; nucleus; apical plasma membrane; extracellular region;
Biological process	cellular response to inorganic substance; intracellular signal transduction; epithelial cilium movement involved in extracellular fluid movement; cyclic nucleotide biosynthetic process; spermatogenesis; positive regulation of apoptotic process; cAMP biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	55811
	271639
	ENSG00000143199
	ENSMUSG00000026567
	Q96PN6
	Q8C0T9
	NM_001167749; NM_001297772; NM_018417
	NM_173029; NM_001357427
	NP_001161221; NP_001284701; NP_060887
	NP_766617; NP_001344356
	Wikidata
View/Edit Human	View/Edit Mouse

Adenylyl cyclase 10 also known as ADCY10 is an enzyme that, in humans, is encoded by the ADCY10 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143199 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026567 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Reed BY, Heller HJ, Gitomer WL, Pak CY (November 1999). "Mapping a gene defect in absorptive hypercalciuria to chromosome 1q23.3-q24". The Journal of Clinical Endocrinology and Metabolism. 84 (11): 3907–3913. doi:10.1210/jcem.84.11.6155. PMID 10566627.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000143199 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026567 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10566627-5] Reed BY, Heller HJ, Gitomer WL, Pak CY (November 1999). "Mapping a gene defect in absorptive hypercalciuria to chromosome 1q23.3-q24". The Journal of Clinical Endocrinology and Metabolism. 84 (11): 3907–3913. doi:10.1210/jcem.84.11.6155. PMID 10566627.

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