| SCF(Fbw7) ubiquitin ligase complex | |||||||
|---|---|---|---|---|---|---|---|
.PNG) | |||||||
| Identifiers | |||||||
| Symbol | Cdh1, Hct1 | ||||||
| PDB | 2ovq | ||||||
| UniProt | P53197 | ||||||
| |||||||
Cdh1 (cdc20 homolog 1) is one of the substrate adaptor proteins of the anaphase-promoting complex (APC) in the budding yeast Saccharomyces cerevisiae. Functioning as an activator of the APC/C, Cdh1 regulates the activity and substrate specificity of this ubiquitin E3-ligase. The human homolog is encoded by the FZR1 gene, which is not to be confused with the CDH1 gene.