ATF7

ATF7
Identifiers
Aliases	ATF7, ATFA, activating transcription factor 7
External IDs	OMIM: 606371; MGI: 2443472; HomoloGene: 4994; GeneCards: ATF7; OMA:ATF7 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	53,626,410 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	102,533,899 bp
RNA expression pattern
	Top expressed in
	popliteal artery; ; tibial arteries; ; gastric mucosa; ; epithelium of colon; ; Descending thoracic aorta; ; minor salivary glands; ; ascending aorta; ; right coronary artery; ; left coronary artery; ; sural nerve;
	Top expressed in
	neural layer of retina; ; muscle of thigh; ; yolk sac; ; lip; ; zygote; ; aortic valve; ; genital tubercle; ; ascending aorta; ; granulocyte; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; enzyme binding; DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; transcription factor binding; protein binding; metal ion binding; mitogen-activated protein kinase binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; nuclear periphery; nucleus; nucleoplasm;
Biological process	viral process; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	11016
	223922
	ENSG00000170653
	ENSMUSG00000099083
	P17544
	Q8R0S1
NM_001130059; NM_001130060; NM_001206682; NM_001206683; NM_006856;
	NM_001366555; NM_001366556; NM_001366558; NM_001366561; NM_001366562; NM_001366563
	NM_146065; NM_001310066; NM_001310067; NM_001310070
NP_001123532; NP_001193611; NP_001193612; NP_006847; NP_001353484;
	NP_001353485; NP_001353487; NP_001353490; NP_001353491; NP_001353492
	NP_001296995; NP_001296996; NP_001296999
	Wikidata
View/Edit Human	View/Edit Mouse

Cyclic AMP-dependent transcription factor ATF-7 is a protein that in humans is encoded by the ATF7 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170653 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000099083 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Gaire M, Chatton B, Kedinger C (Aug 1990). "Isolation and characterization of two novel, closely related ATF cDNA clones from HeLa cells". Nucleic Acids Res. 18 (12): 3467–73. doi:10.1093/nar/18.12.3467. PMC 330998. PMID 1694576.
^ Peters CS, Liang X, Li S, Kannan S, Peng Y, Taub R, Diamond RH (Apr 2001). "ATF-7, a novel bZIP protein, interacts with the PRL-1 protein-tyrosine phosphatase". J Biol Chem. 276 (17): 13718–26. doi:10.1074/jbc.M011562200. PMID 11278933.
^ "Entrez Gene: ATF7 activating transcription factor 7".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170653 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000099083 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1694576-5] Gaire M, Chatton B, Kedinger C (Aug 1990). "Isolation and characterization of two novel, closely related ATF cDNA clones from HeLa cells". Nucleic Acids Res. 18 (12): 3467–73. doi:10.1093/nar/18.12.3467. PMC 330998. PMID 1694576.

[pmid11278933-6] Peters CS, Liang X, Li S, Kannan S, Peng Y, Taub R, Diamond RH (Apr 2001). "ATF-7, a novel bZIP protein, interacts with the PRL-1 protein-tyrosine phosphatase". J Biol Chem. 276 (17): 13718–26. doi:10.1074/jbc.M011562200. PMID 11278933.

[entrez-7] "Entrez Gene: ATF7 activating transcription factor 7".

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