Abagovomab

Abagovomab
Monoclonal antibody
TypeWhole antibody
SourceMouse
Target(imitates CA-125)
Clinical data
Pregnancy
category
  • N/A
Routes of
administration
subcutaneous
ATC code
  • none
Pharmacokinetic data
BioavailabilityN/A
ExcretionN/A
Identifiers
CAS Number
ChemSpider
  • none
UNII
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Abagovomab is a mouse anti-idiotype monoclonal antibody whose variable epitope mirrors a tumour antigen (CA-125) highly expressed in the epithelial ovarian cancer. Abagovomab does not bind directly to CA-125, but it works as a "surrogate" antigen, enabling the immune system to identify and attack tumour cells displaying the CA-125 protein. Through this, it is hoped that the body's immune system may be able to combat any remaining individual tumour cells and thus prevent recurrence of the disease.[medical citation needed]