Monoclonal antibody | |
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Type | Whole antibody |
Source | Mouse |
Target | (imitates CA-125) |
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Routes of administration | subcutaneous |
ATC code |
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Pharmacokinetic data | |
Bioavailability | N/A |
Excretion | N/A |
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ChemSpider |
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Abagovomab is a mouse anti-idiotype monoclonal antibody whose variable epitope mirrors a tumour antigen (CA-125) highly expressed in the epithelial ovarian cancer. Abagovomab does not bind directly to CA-125, but it works as a "surrogate" antigen, enabling the immune system to identify and attack tumour cells displaying the CA-125 protein. Through this, it is hoped that the body's immune system may be able to combat any remaining individual tumour cells and thus prevent recurrence of the disease.[medical citation needed]