Acetalated dextran

Acetalated dextran
Names
IUPAC name
varies
Other names
Ac-DEX, Ace-DEX, modified dextran
Identifiers
ChemSpider
  • none
Properties
Molar mass varies
Appearance white powder
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Acetalated dextran is a biodegradable polymer based on dextran that has acetal modified hydroxyl groups. After synthesis, the hydrophilic polysaccharide dextran is rendered insoluble in water, but soluble in organic solvents. This allows it to be processed in the same manner as many polyesters, like poly(lactic-co-glycolic acid), through processes like solvent evaporation and emulsion.[1] Acetalated dextran is structurally different from acetylated dextran.

  1. ^ Bachelder, EM; Pino, EN; Ainslie, KM (Feb 2017). "Acetalated Dextran: A Tunable and Acid-Labile Biopolymer with Facile Synthesis and a Range of Applications". Chem Rev. 117 (3): 1915–1926. doi:10.1021/acs.chemrev.6b00532. PMID 28032507.