Acetoacetic ester synthesis

Acetoacetic ester synthesis
Reaction type Coupling reaction
Reaction
Acetoacetic acid esters
+
R-X
+
(-O-R & H3O+)
α-substituted acetone
Conditions
Temperature
Identifiers
Organic Chemistry Portal acetoacetic-ester-synthesis
RSC ontology ID RXNO:0000107

Acetoacetic ester synthesis is a chemical reaction where ethyl acetoacetate is alkylated at the α-carbon to both carbonyl groups and then converted into a ketone, or more specifically an α-substituted acetone. This is very similar to malonic ester synthesis.

Acetoacetic ester synthesis equation
Acetoacetic ester synthesis equation