Acetonide

General structure of a 1,2-acetonide. The diol is shown in blue, the acetone part in red.

In organic chemistry, an acetonide is the functional group composed of the cyclic ketal of a diol with acetone. The more systematic name for this structure is an isopropylidene ketal. Acetonide is a common protecting group for 1,2- and 1,3-diols.[1] The protecting group can be removed by hydrolysis of the ketal using dilute aqueous acid.

  1. ^ Kocieński, Philip j. (1994). "3.2.2: Diol Protecting Groups—Acetals—Isopropylidene Acetals". Protecting Groups. Foundations of Organic Chemistry Series. Thieme Medical Publishers. p. 103.