Actinomyces bovis

Actinomyces bovis
High-magnification micrograph of a "sulfur" granule formed by Actinomyces in the mandible, H&E stain
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Actinomycetota
Class: Actinomycetia
Order: Actinomycetales
Family: Actinomycetaceae
Genus: Actinomyces
Species:
A. bovis
Binomial name
Actinomyces bovis
Harz 1877 (Approved Lists 1980)[1]
Type strain
ATCC 13683[2]
CCUG 31996
CIP 103258
DSM 43014
NCTC 11535

Actinomyces bovis is a branching, Gram-positive, rod-shaped bacterium of the genus Actinomyces.[1] It is the causative agent of lumpy jaw in cattle, and occasionally causes actinomycosis infections in humans.[3] A. bovis normally populates the gastrointestinal tract of healthy ruminants, but is opportunistic in nature and will move into tissues through ulcerations or abrasions of the mucosa to cause infection.[4] The disease occurs when there is physical damage to the tissue of the mouth, allowing the bacteria to colonize the deep tissue and bone, typically affecting the mandible and maxilla.[5] Actinomycosis is pathognomonic for abscesses containing "sulfur" granules, and its colonies appear basophilic with club-shaped reaction products on a histological preparation.[6][7] Lumpy jaw is commonly treated with broad-spectrum antibiotics with varying success,[8] and can be a major economic loss for producers in countries where it is endemic.[9] Because this organism is zoonotic, it is a human health concern and can cause granulomas, abscesses, skin lesions, and bronchopneumonia.[4]

  1. ^ a b L Pine; A Howell; SJ Watson (1960). "Studies of the Morphological, Physiological, and Biochemical Characters of Actinomyces bovis". J Gen Microbiol. 23 (3): 403–424. doi:10.1099/00221287-23-3-403. PMID 13735815.
  2. ^ Euzéby JP, Parte AC. "Actinomyces bovis". List of Prokaryotic names with Standing in Nomenclature (LPSN). Retrieved May 11, 2022.
  3. ^ P Mansouri; S Farshi; A Khosravi; ZS Naraghi (2011). "Primary cutaneous actinomycosis caused by Actinomyces bovis in a patient with common variable immunodeficiency". The Journal of Dermatology. 38 (38): 911–915. doi:10.1111/j.1346-8138.2010.01165.x. PMID 21658111. S2CID 20116978.
  4. ^ a b Underwood, Wendy J. (2015). Laboratory Animal Medicine (Third ed.). Elsevier Inc. ISBN 978-0-12-409527-4.
  5. ^ Admin (2018-02-22). "Painful lumpy jaw disease requires intervention". The Western Producer. Retrieved 2020-09-13.
  6. ^ Farooq, U (2010). "Field Surgical Intervention of Bovine Actinomycosis". Pakistan Veterinary Journal.
  7. ^ Masand, A. (2015). "Actinomycosis (lumpy Jaw) in Cow: A Case Report". Comparative Clinical Pathology. 24 (3): 541–543. doi:10.1007/s00580-014-1939-1. S2CID 31970732.
  8. ^ Color Atlas of Diseases and Disorders of Cattle - Pages 261-267. Mosby. 2011-01-01. p. 63. doi:10.1016/b978-0-7234-3602-7.00021-2. ISBN 978-0-7234-3602-7.
  9. ^ Luisa, Bozzano G. (2012-12-02). Actinomycetes in Biotechnology. Elsevier. ISBN 978-0-08-098433-9.