Adenoviral keratoconjunctivitis

Keratoconjunctivitis
Other namesKeratoconjunctivitis epidemica
Adenoviral Keratoconjunctivitis
SpecialtyOphthalmology, infectious diseases
SymptomsRed eye, discomfort/irritation, sensitivity to light, watering, blurred vision, discharge[1]
ComplicationsCorneal scarring[2]
Usual onsetSudden in an adult[3]
Duration7–10 days, can be longer[3]
CausesAdenoviruses, commonly types 8 and 37[3]
Diagnostic methodVisualisation, viral culture (with immunofluorescence staining), PCR[3]
Differential diagnosisHerpes simplex type I, acanthamoeba, fungal infection[4]
PreventionHand washing[3]
TreatmentCold compress, artificial tears[2]
FrequencyEpidemics, common, adults>children[2]

Adenoviral keratoconjunctivitis, also known as epidemic keratoconjunctivitis, is a contagious eye infection, a type of adenovirus disease caused by adenoviruses.[1] It typically presents as a conjunctivitis with a sudden onset of a painful red eye, watery discharge and feeling that something is in the eye.[3] Photophobia develops with blurred vision and lymphadenopathy by the ear nearest the affected eye.[2] It is often associated with a sore throat and stuffy and runny nose, mainly in adults.[3] A type of adenoviral keratoconjunctivitis in very young children can present with a high fever, sore throat, ear infection, vomiting and diarrhea.[3]

It is commonly caused by types 8 and 37 adenoviruses, spread by contaminated eye examination instruments and eye solutions, touching eyes by infected people, from inadequately chlorinated swimming pools, or other contaminated objects.[3] The incubation period is around five to 10 days.[3]

Usually, the condition is better after a week to 10 days without treatment.[3] Cold compresses and artificial tears may help.[2] Corneal scarring occurs in up to half of cases and the blurred vision may continue for a long time in some people.[2] The virus may remain in the eye for 2–3 years after recovering.[3]

It is a common cause of a red eye and tends to occur in large numbers of people at the same time.[2] Adults tend to be affected more frequently than children.[3]

  1. ^ a b Burrow, Michael K.; Patel, Bhupendra C. (2022). "Keratoconjunctivitis". StatPearls. StatPearls Publishing. PMID 31194419.
  2. ^ a b c d e f g Bawazeer, Ahmed (4 June 2019). "Epidemic Keratoconjunctivitis (EKC)". Medscape. Archived from the original on 21 April 2021. Retrieved 16 July 2021.
  3. ^ a b c d e f g h i j k l m Shieh, Wun-Ju (10 September 2021). "Human adenovirus infections in pediatric population - An update on clinico-pathologic correlation". Biomedical Journal. 45 (1): S2319–4170(21)00109–8. doi:10.1016/j.bj.2021.08.009. ISSN 2320-2890. PMC 9133246. PMID 34506970. S2CID 237479412.
  4. ^ Cite error: The named reference pih was invoked but never defined (see the help page).