Adipiodone

Adipiodone
Clinical data
Trade names	Cholografin, Biligrafin
Other names	3-[[6-[(3-Carboxy-2,4,6-triiodophenyl)amino]-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid
ATC code	V08AC04 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 3-{5-[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]pentanamido}-2,4,6-triiodobenzoic acid;
CAS Number	606-17-7 ;
PubChem CID	3739;
IUPHAR/BPS	7400;
DrugBank	DB04711 ;
ChemSpider	3608 ;
UNII	TKQ858A3VW;
KEGG	D01774 ;
ChEBI	CHEBI:31176;
ChEMBL	ChEMBL1165268 ;
CompTox Dashboard (EPA)	DTXSID6023153 ;
ECHA InfoCard	100.009.187
Chemical and physical data
Formula	C20H14I6N2O6
Molar mass	1139.767 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(Nc1c(I)c(c(I)cc1I)C(=O)O)CCCCC(=O)Nc2c(I)c(C(=O)O)c(I)cc2I;
	InChI InChI=1S/C20H14I6N2O6/c21-7-5-9(23)17(15(25)13(7)19(31)32)27-11(29)3-1-2-4-12(30)28-18-10(24)6-8(22)14(16(18)26)20(33)34/h5-6H,1-4H2,(H,27,29)(H,28,30)(H,31,32)(H,33,34) ; Key:FFINMCNLQNTKLU-UHFFFAOYSA-N ;
	(verify)

Adipiodone (INN, or iodipamide; trade names Cholografin and Biligrafin) is a pharmaceutical drug used as a radiocontrast agent in X-ray imaging. It was introduced in the 1950s.^[1]^[2]

^ Hastings-James R, Glazebrook AJ (April 1955). "Cholografin". Canadian Medical Association Journal. 72 (8): 561–5. PMC 1825662. PMID 14364399.
^ Dilger SK, Nelson N, Venkatesh SK, Ehman EC, Fidler JL, Fletcher JG, et al. (September 2019). "Computed Tomography Cholangiography Using the Magnetic Resonance Contrast Agent Gadoxetate Disodium: A Phantom Study". Investigative Radiology. 54 (9): 572–579. doi:10.1097/RLI.0000000000000580. PMID 31261292. S2CID 195772743.

[1] Hastings-James R, Glazebrook AJ (April 1955). "Cholografin". Canadian Medical Association Journal. 72 (8): 561–5. PMC 1825662. PMID 14364399.

[2] Dilger SK, Nelson N, Venkatesh SK, Ehman EC, Fidler JL, Fletcher JG, et al. (September 2019). "Computed Tomography Cholangiography Using the Magnetic Resonance Contrast Agent Gadoxetate Disodium: A Phantom Study". Investigative Radiology. 54 (9): 572–579. doi:10.1097/RLI.0000000000000580. PMID 31261292. S2CID 195772743.

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