Affymetrix

"Affy" redirects here. For the confectionery, see Affy Tapple. For the school, see Affies.
Affymetrix, Inc.
Company typeSubsidiary
IndustryBiotechnology
Founded1992
HeadquartersSanta Clara, California, U.S.
Number of locations
11
Key people
Stephen Fodor, Frank Witney (CEO)
RevenueIncrease US$327 Million (FY 2009)[1]
Decrease US$-30.6 Million (FY 2009)[1]
Decrease US$-23.9 Million (FY 2009)[1]
Total assetsDecrease US$612 Million (FY 2009)[2]
Total equityDecrease US$288 Million (FY 2009)[2]
Number of employees
1,141[3]
ParentThermo Fisher Scientific
Websitehttps://www.thermofisher.com/us/en/home/life-science/microarray-analysis.html

Affymetrix is now Applied Biosystems, a brand of DNA microarray products sold by Thermo Fisher Scientific that originated with an American biotechnology research and development and manufacturing company of the same name.[4] The Santa Clara, California-based Affymetrix, Inc. now a part of Thermo Fisher Scientific was co-founded by Alex Zaffaroni and Stephen Fodor. Stephen Fodor and his group, based on their earlier development of methods to fabricate DNA microarrays using semiconductor manufacturing techniques.[5][6]

In 1994, the company's first product under the "GeneChip" Affymetrix trademark, an HIV genotyping chip was introduced,[7] and the company went public in 1996.[8]

After incorporation, Affymetrix grew in part by acquiring technologies from other companies, including Genetic MicroSystems (slide-based Microarrays and scanners)[citation needed] and Neomorphic (for bioinformatics) in 2000,[9] ParAllele Bioscience (custom SNP genotyping),[citation needed] USB/Anatrace (biochemical reagents) in 2008,[10] Panomics (low to mid-plex applications) in 2008,[citation needed] and eBioscience (flow cytometry) in 2012.[11] Affymetrix spun off Perlegen Sciences in 2000,[12][13] as a discrete business focusing on wafer-scale genomics to characterize population-variance of genomic markers.[14]

In January 2014, the Food and Drug Administration approved Affymetrix's postnatal blood test, CytoScan Dx Assay, looking at whole-genome correlates of congenital abnormalities and other causes of childhood developmental delay.[15]

On January 8, 2016, Thermo Fisher Scientific announced its acquisition of Affymetrix for approximately $1.3 billion,[16] which closed on March 31, 2016.[17]

  1. ^ a b c Affymetrix (AFFX) annual SEC income statement filing via Wikinvest
  2. ^ a b Affymetrix (AFFX) annual SEC balance sheet filing via Wikinvest
  3. ^ "Company Profile for Affymetrix Inc (AFFX)". Archived from the original on 2012-03-01. Retrieved 2008-10-20.
  4. ^ "Thermo Fisher Scientific to acquire Affymetrix". Grainews. Retrieved 2022-03-23.
  5. ^ "Affymetrix and Illumina Settle Their Patent Disputes". fiercebiotech.com. 10 January 2008. Retrieved 2022-01-12.
  6. ^ "Stephen Fodor, Jami Nachtsheim". genomeweb.com. 30 January 2015. Retrieved 2022-01-12.
  7. ^ "Affymetrix and bioMérieux Extend Their Agreement on GeneChip® Technology to Breast Cancer Diagnostics". biomerieux.com. Retrieved 2022-01-12.
  8. ^ "AFFX Meaning AFFX Stock Meaning". acronym.io. Retrieved 2022-01-12.
  9. ^ "Affymetrix to Acquire Neomorphic In a Deal Valued at $70 Million". Wall Street Journal. 2 October 2000. Retrieved 2022-01-14.
  10. ^ "Affymetrix Sells Anatrace Unit to Investment Firm StoneCalibre". genomeweb.com. 15 October 2013. Retrieved 2022-01-28.
  11. ^ "Affymetrix Completes eBioscience Acquisition". genomeweb.com. 26 June 2012. Retrieved 2022-02-02.
  12. ^ "Perlegen Signs Its First Big Pharma Deal with GlaxoSmithKline, Finishes Fifty Genomes". genomeweb.com. 27 September 2002. Retrieved 2022-02-02.
  13. ^ "National Library of Medicine". Retrieved 2024-09-19.
  14. ^ "A Guide to HIV-1 Reverse Transcriptase and Protease Sequencing for Drug Resistance Studies" (PDF). hivdb.stanford.edu. Retrieved 2022-02-09.
  15. ^ "FDA OKs Postnatal Blood Test for Intellectual Disabilities". medscape.com. Retrieved 2022-02-09.
  16. ^ Armental, Maria (8 January 2016). "Thermo Fisher Scientific to Buy Affymetrix in $1.3 Billion Cash Deal". The Wall Street Journal. Retrieved 14 January 2016.
  17. ^ "Thermo Fisher Scientific Completes Acquisition of Affymetrix Following Approval of Transaction by Affymetrix Stockholders". ir.thermofisher.com.