Aldo-keto reductase

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary
PDB	1a80, 1abn, 1ads, 1ae4, 1afs, 1ah0, 1ah3, 1ah4, 1az1, 1az2, 1c9w, 1cwn, 1dla, 1ef3, 1eko, 1el3, 1exb, 1frb, 1gve, 1hqt, 1hw6, 1iei, 1ihi, 1j96, 1jez, 1k8c, 1lqa, 1lwi, 1m9h, 1mar, 1mi3, 1mrq, 1mzr, 1og6, 1pwl, 1pwm, 1pyf, 1pz0, 1pz1, 1q13, 1q5m, 1qrq, 1qwk, 1r38, 1ral, 1ry0, 1ry8, 1s1p, 1s1r, 1s2a, 1s2c, 1sm9, 1t40, 1t41, 1ur3, 1us0, 1vbj, 1vp5, 1x96, 1x97, 1x98, 1xf0, 1xgd, 1xjb, 1ye4, 1ye6, 1z3n, 1z89, 1z8a, 1z9a, 1zgd, 1zq5, 1zsx, 2a79, 2acq, 2acr, 2acs, 2acu, 2agt, 2alr, 2bgq, 2bgs, 2bp1, 2c91, 2clp, 2dux, 2duz, 2dv0, 2f2k, 2f38, 2fgb, 2fvl, 2fz8, 2fz9, 2fzb, 2fzd, 2hdj, 2he5, 2he8, 2hej, 2hv5, 2hvn, 2hvo, 2i16, 2i17, 2ikg, 2ikh, 2iki, 2ikj, 2ine, 2inz, 2ipf, 2ipg, 2ipj, 2ipw, 2iq0, 2iqd, 2is7, 2isf, 2j8t, 2nvc, 2nvd, 2p5n, 2pd5, 2pd9, 2pdb, 2pdc, 2pdf, 2pdg, 2pdh, 2pdi, 2pdj, 2pdk, 2pdl, 2pdm, 2pdn, 2pdp, 2pdq, 2pdu, 2pdw, 2pdx, 2pdy, 2pev, 2pf8, 2pfh, 2pzn, 2qxw, 2r9r, 2vdg, 3bcj, 3bur, 3buv, 3bv7, 3c3u, 3cmf, 3cot, 3eau

Aldo/keto reductase family
Aldo/keto reductase family
	Ribbon diagram of human aldose reductase in complex with NADP+, citrate, and IDD594, a small molecule inhibitor. From PDB: 1us0.
Identifiers
Symbol	Aldo_ket_red
Pfam	PF00248
InterPro	IPR001395
PROSITE	PDOC00061
SCOP2	1ads / SCOPe / SUPFAM
CDD	cd06660
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary
PDB	1a80, 1abn, 1ads, 1ae4, 1afs, 1ah0, 1ah3, 1ah4, 1az1, 1az2, 1c9w, 1cwn, 1dla, 1ef3, 1eko, 1el3, 1exb, 1frb, 1gve, 1hqt, 1hw6, 1iei, 1ihi, 1j96, 1jez, 1k8c, 1lqa, 1lwi, 1m9h, 1mar, 1mi3, 1mrq, 1mzr, 1og6, 1pwl, 1pwm, 1pyf, 1pz0, 1pz1, 1q13, 1q5m, 1qrq, 1qwk, 1r38, 1ral, 1ry0, 1ry8, 1s1p, 1s1r, 1s2a, 1s2c, 1sm9, 1t40, 1t41, 1ur3, 1us0, 1vbj, 1vp5, 1x96, 1x97, 1x98, 1xf0, 1xgd, 1xjb, 1ye4, 1ye6, 1z3n, 1z89, 1z8a, 1z9a, 1zgd, 1zq5, 1zsx, 2a79, 2acq, 2acr, 2acs, 2acu, 2agt, 2alr, 2bgq, 2bgs, 2bp1, 2c91, 2clp, 2dux, 2duz, 2dv0, 2f2k, 2f38, 2fgb, 2fvl, 2fz8, 2fz9, 2fzb, 2fzd, 2hdj, 2he5, 2he8, 2hej, 2hv5, 2hvn, 2hvo, 2i16, 2i17, 2ikg, 2ikh, 2iki, 2ikj, 2ine, 2inz, 2ipf, 2ipg, 2ipj, 2ipw, 2iq0, 2iqd, 2is7, 2isf, 2j8t, 2nvc, 2nvd, 2p5n, 2pd5, 2pd9, 2pdb, 2pdc, 2pdf, 2pdg, 2pdh, 2pdi, 2pdj, 2pdk, 2pdl, 2pdm, 2pdn, 2pdp, 2pdq, 2pdu, 2pdw, 2pdx, 2pdy, 2pev, 2pf8, 2pfh, 2pzn, 2qxw, 2r9r, 2vdg, 3bcj, 3bur, 3buv, 3bv7, 3c3u, 3cmf, 3cot, 3eau

The aldo-keto reductase family is a family of proteins that are subdivided into 16 categories; these include a number of related monomeric NADPH-dependent oxidoreductases, such as aldehyde reductase, aldose reductase, prostaglandin F synthase, xylose reductase, rho crystallin, and many others.^[1]