Protein-coding gene in the species Homo sapiens
Aldolase C, fructose-bisphosphate (ALDOC , or ALDC ), is an enzyme that, in humans, is encoded by the ALDOC gene on chromosome 17. This gene encodes a member of the class I fructose-bisphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose 1,6-bisphosphate and fructose-1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde 3-phosphate or glyceraldehyde , respectively.[provided by RefSeq, Jul 2008][ 5] [ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000109107 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017390 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Entrez Gene: ALDOC aldolase C, fructose-bisphosphate" .
^ Rocchi M, Vitale E, Covone A, Romeo G, Santamaria R, Buono P, Paolella G, Salvatore F (June 1989). "Assignment of human aldolase C gene to chromosome 17, region cen----q21.1". Human Genetics . 82 (3): 279–82. doi :10.1007/BF00291170 . PMID 2731939 . S2CID 7980799 .