Aldolase C

ALDOC
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesALDOC, ALDC, Aldolase C, aldolase, fructose-bisphosphate C
External IDsOMIM: 103870; MGI: 101863; HomoloGene: 21073; GeneCards: ALDOC; OMA:ALDOC - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005165

NM_009657
NM_001303423

RefSeq (protein)

NP_005156

NP_001290352
NP_033787

Location (UCSC)Chr 17: 28.57 – 28.58 MbChr 11: 78.21 – 78.22 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Aldolase C, fructose-bisphosphate (ALDOC, or ALDC), is an enzyme that, in humans, is encoded by the ALDOC gene on chromosome 17. This gene encodes a member of the class I fructose-bisphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose 1,6-bisphosphate and fructose-1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde 3-phosphate or glyceraldehyde, respectively.[provided by RefSeq, Jul 2008][5][6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000109107Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017390Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: ALDOC aldolase C, fructose-bisphosphate".
  6. ^ Rocchi M, Vitale E, Covone A, Romeo G, Santamaria R, Buono P, Paolella G, Salvatore F (June 1989). "Assignment of human aldolase C gene to chromosome 17, region cen----q21.1". Human Genetics. 82 (3): 279–82. doi:10.1007/BF00291170. PMID 2731939. S2CID 7980799.