Alternative vaccination schedule

In the United States, an alternative vaccination schedule is a vaccination schedule differing from the schedule endorsed by the Advisory Committee on Immunization Practices (ACIP).[1] These schedules may be either written or ad hoc, and have not been tested for their safety or efficacy.[2][3] Proponents of such schedules aim to reduce the risk of adverse effects they believe to be caused by vaccine components, such as "immune system overload" that is argued to be caused by exposure to multiple antigens.[4] Parents who adopt these schedules tend to do so because they are concerned about the potential risks of vaccination, rather than because they are unaware of the significance of vaccination's benefits.[5] Delayed vaccination schedules have been shown to lead to an increase in breakthrough infections without any benefit in lower side effect profiles.[6][7][8]

  1. ^ Opel, Douglas J.; Banerjee, Ashmita; Taylor, James A. (October 2013). "Use of alternative childhood immunization schedules in King County, Washington, USA". Vaccine. 31 (42): 4699–4701. doi:10.1016/j.vaccine.2013.08.036. PMID 23981431.
  2. ^ Opel, Douglas J.; Marcuse, Edgar K. (1 March 2013). "The Enigma of Alternative Childhood Immunization Schedules". JAMA Pediatrics. 167 (3): 304–5. doi:10.1001/jamapediatrics.2013.786. PMID 23338852.
  3. ^ Boom, Julie; Cunningham, Rachel (2014). Understanding and Managing Vaccine Concerns. Springer. pp. 8–9. ISBN 9783319075631.
  4. ^ Cite error: The named reference jackson was invoked but never defined (see the help page).
  5. ^ Healy, C. Mary; Montesinos, Diana P.; Middleman, Amy B. (January 2014). "Parent and provider perspectives on immunization: Are providers overestimating parental concerns?". Vaccine. 32 (5): 579–584. doi:10.1016/j.vaccine.2013.11.076. PMID 24315883.
  6. ^ Kroger A, Bahta L, Hunter P. Best Practices Guidance of the Advisory Committee on Immunization Practices (ACIP).
  7. ^ Offit, Paul A.; Hackett, Charles J. (1 March 2003). "Addressing Parents' Concerns: Do Vaccines Cause Allergic or Autoimmune Diseases?". Pediatrics. 111 (3): 653–659. doi:10.1542/peds.111.3.653. PMID 12612250. S2CID 10695185.
  8. ^ Offit, Paul A.; Davis, Robert L.; Gust, Deborah (2008). "Vaccine safety". Vaccines: 1629–1650. doi:10.1016/B978-1-4160-3611-1.50078-7. ISBN 9781416036111.