Amlexanox

Amlexanox

Clinical data
Trade names	Aphthasol
AHFS/Drugs.com	Monograph
MedlinePlus	a601017
Routes of administration	Topical
ATC code	A01AD07 (WHO) R03DX01 (WHO)
Pharmacokinetic data
Elimination half-life	3.5 hours
Excretion	Renal (17%)
Identifiers
IUPAC name 2-amino-7-isopropyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid
CAS Number	68302-57-8 Y
PubChem CID	2161
IUPHAR/BPS	7113
DrugBank	DB01025 Y
ChemSpider	2076 Y
UNII	BRL1C2459K
KEGG	D01828 Y
ChEBI	CHEBI:31205 Y
ChEMBL	ChEMBL1096 Y
CompTox Dashboard (EPA)	DTXSID2022595
ECHA InfoCard	100.230.878
Chemical and physical data
Formula	C16H14N2O4
Molar mass	298.298 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C1c3cc(ccc3Oc2nc(c(cc12)C(=O)O)N)C(C)C
InChI InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21) Y Key:SGRYPYWGNKJSDL-UHFFFAOYSA-N Y
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Amlexanox (trade name Aphthasol) is an anti-inflammatory antiallergic immunomodulator used to treat recurrent aphthous ulcers (canker sores), and (in Japan) several inflammatory conditions. This drug has been discontinued in the U.S.^[1]