Amotivational syndrome is a chronic psychiatric disorder characterized by signs that are linked to cognitive and emotional states such as detachment, blunted emotion and drives, executive functions like memory and attention,[1] disinterest, passivity, apathy, and a general lack of motivation.[2][3] This syndrome can be branched into two subtypes: marijuana amotivational syndrome, or cannabis-induced amotivational syndrome, which is caused by usage of or dependency on that substance, and is primarily associated with long-term effects of cannabis use,[1] and SSRI-induced amotivational syndrome or SSRI-induced apathy, caused by the intake of SSRI medication dosage.[4][5] According to the Handbook of Clinical Psychopharmacology for Therapists, amotivational syndrome is listed as a possible side effect of SSRIs in the treatment of clinical depression.[6] It is a disorder of diminished motivation.
^ abRovai, L; Maremmani, AG; Pacini, M; Pani, PP; Rugani, F; Lamanna, F; Schiavi, E; Mautone, S; Dell'Osso, L; Maremmani, I (2013). "Negative dimension in psychiatry. Amotivational syndrome as a paradigm of negative symptoms in substance abuse". Rivista di Psichiatria. 48 (1): 1–9. doi:10.1708/1228.13610. PMID23438696. S2CID7099936.