Amotivational syndrome

Amotivational syndrome
SpecialtyPsychiatry

Amotivational syndrome is a chronic psychiatric disorder characterized by signs that are linked to cognitive and emotional states such as detachment, blunted emotion and drives, executive functions like memory and attention,[1] disinterest, passivity, apathy, and a general lack of motivation.[2][3] This syndrome can be branched into two subtypes: marijuana amotivational syndrome, or cannabis-induced amotivational syndrome, which is caused by usage of or dependency on that substance, and is primarily associated with long-term effects of cannabis use,[1] and SSRI-induced amotivational syndrome or SSRI-induced apathy, caused by the intake of SSRI medication dosage.[4][5] According to the Handbook of Clinical Psychopharmacology for Therapists, amotivational syndrome is listed as a possible side effect of SSRIs in the treatment of clinical depression.[6] It is a disorder of diminished motivation.

  1. ^ a b Rovai, L; Maremmani, AG; Pacini, M; Pani, PP; Rugani, F; Lamanna, F; Schiavi, E; Mautone, S; Dell'Osso, L; Maremmani, I (2013). "Negative dimension in psychiatry. Amotivational syndrome as a paradigm of negative symptoms in substance abuse". Rivista di Psichiatria. 48 (1): 1–9. doi:10.1708/1228.13610. PMID 23438696. S2CID 7099936.Open access icon
  2. ^ Garland, E. Jane; Baerg, Elizabeth A. (2001-06-01). "Amotivational Syndrome Associated with Selective Serotonin Reuptake Inhibitors in Children and Adolescents". Journal of Child and Adolescent Psychopharmacology. 11 (2): 181–186. doi:10.1089/104454601750284090. ISSN 1044-5463. PMID 11436958.
  3. ^ Castaño, Guillermo A.; Becoña, Elisardo; Restrepo, Sandra Milena; Scoppetta, Orlando (2020-04-01). "Toward the Design and Validation of a Scale to Assess Amotivational Syndrome in Chronic Marijuana Users (ESATHC)". International Journal of Mental Health and Addiction. 18 (2): 305–313. doi:10.1007/s11469-019-00132-y. ISSN 1557-1882. S2CID 207990165.
  4. ^ Lac, Andrew; Luk, Jeremy W. (2018-02-01). "Testing the Amotivational Syndrome: Marijuana Use Longitudinally Predicts Lower Self-Efficacy Even After Controlling for Demographics, Personality, and Alcohol and Cigarette Use". Prevention Science. 19 (2): 117–126. doi:10.1007/s11121-017-0811-3. ISSN 1573-6695. PMC 5732901. PMID 28620722.
  5. ^ Sansone, Randy A.; Sansone, Lori A. (October 2010). "SSRI-Induced Indifference". Psychiatry (Edgmont). 7 (10): 14–18. ISSN 1550-5952. PMC 2989833. PMID 21103140.
  6. ^ Preston, John; John, O'Neal; Mary, Talaga (2013). Handbook of Clinical Psychopharmacology for Therapists (7th ed.). New Harbinger Publications. p. 193. ISBN 978-1608826643.