Anaplasma phagocytophilum | |
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Human HL60 cells containing Anaplasma phagocytophilum (indicated by arrows) which are basophilic intracytoplasmic inclusions when stained with Wright-Giemsa stain | |
Scientific classification | |
Domain: | Bacteria |
Phylum: | Pseudomonadota |
Class: | Alphaproteobacteria |
Order: | Rickettsiales |
Family: | Ehrlichiaceae |
Genus: | Anaplasma |
Species: | A. phagocytophilum
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Binomial name | |
Anaplasma phagocytophilum (Foggie 1949) Dumler et al. 2001[1]
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Synonyms | |
Rickettsia phagocytophila ovis |
Anaplasma phagocytophilum (formerly Ehrlichia phagocytophilum)[2] is a Gram-negative bacterium that is unusual in its tropism to neutrophils. It causes anaplasmosis in sheep and cattle, also known as tick-borne fever and pasture fever, and also causes the zoonotic disease human granulocytic anaplasmosis.[3]
A. phagocytophilum is a Gram-negative, obligate bacterium of neutrophils. It causes human granulocytic anaplasmosis, which is a tick-borne rickettsial disease. Because this bacterium invades neutrophils, it has a unique adaptation and pathogenetic mechanism.[4]