Anaplastic lymphoma kinase

ALK
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesALK, CD246, NBLST3, anaplastic lymphoma receptor tyrosine kinase, ALK receptor tyrosine kinase, ALK (gene), ALK1
External IDsOMIM: 105590; MGI: 103305; HomoloGene: 68387; GeneCards: ALK; OMA:ALK - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004304
NM_001353765

NM_007439

RefSeq (protein)

NP_004295
NP_001340694

NP_031465

Location (UCSC)Chr 2: 29.19 – 29.92 MbChr 17: 72.18 – 72.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Anaplastic lymphoma kinase (ALK) also known as ALK tyrosine kinase receptor or CD246 (cluster of differentiation 246) is an enzyme that in humans is encoded by the ALK gene.[5][6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171094Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000055471Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Morris SW, Kirstein MN, Valentine MB, Dittmer KG, Shapiro DN, Saltman DL, et al. (March 1994). "Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma". Science. 263 (5151): 1281–1284. Bibcode:1994Sci...263.1281M. doi:10.1126/science.8122112. PMID 8122112.
  6. ^ "Entrez Gene: ALK anaplastic lymphoma kinase (Ki-1)".