Angiofibroma

Angiofibroma
Angiofibroma, Hematoxylin and eosin stain, magnification ×10.
Specialty	Oncology
Symptoms	Itchiness and sometimes bleeding.[1]
Complications	Facial disfigurement and stigmatization.[1]
Causes	Local overgrowth of collagen, fibroblasts, and blood vessels.[1]
Risk factors	Tuberous sclerosis, Birt-Hogg-Dubé syndrome, and Multiple endocrine neoplasia type 1.[1]
Diagnostic method	Skin biopsy.[1]
Differential diagnosis	Intradermal melanocytic naevus, Acne, Basal cell carcinoma, Viral warts, Subungual exostosis, Molluscum contagiosum, and Anogenital warts.[1]
Treatment	Excision, Dermabrasion, Using lasers, electrical, and radiofrequency devices, Cryotherapy, Topical podophyllotoxin, Topical rapamycin, and Topical beta-blockers.[1]

Angiofibroma (AGF) is a descriptive term for a wide range of benign skin or mucous membrane (i.e. the outer membrane lining body cavities such as the mouth and nose) lesions in which individuals have:

1. benign papules, i.e. pinhead-sized elevations that lack visible evidence of containing fluid;
2. nodules, i.e. small firm lumps usually >0.1 cm in diameter; and/or
3. tumors, i.e. masses often regarded as ~0.8 cm or larger.