Angiomotin-like protein 1

AMOTL1
Identifiers
Aliases	AMOTL1, JEAP, angiomotin like 1
External IDs	OMIM: 614657; MGI: 1922973; HomoloGene: 43977; GeneCards: AMOTL1; OMA:AMOTL1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	94,876,748 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	14,556,352 bp
RNA expression pattern
	Top expressed in
	tibialis anterior muscle; ; deltoid muscle; ; Skeletal muscle tissue of rectus abdominis; ; cardiac muscle tissue of right atrium; ; tendon of biceps brachii; ; body of tongue; ; tibia; ; quadriceps femoris muscle; ; skin of arm; ; vastus lateralis muscle;
	Top expressed in
	hand; ; knee joint; ; foot; ; soleus muscle; ; temporal muscle; ; lateral geniculate nucleus; ; medial head of gastrocnemius muscle; ; triceps brachii muscle; ; sternocleidomastoid muscle; ; quadriceps femoris muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; identical protein binding;
Cellular component	COP9 signalosome; cytosol; apical plasma membrane; cytoplasmic vesicle; lamellipodium; bicellular tight junction; cell junction;
Biological process	establishment of cell polarity involved in ameboidal cell migration; Wnt signaling pathway; hippo signaling; positive regulation of blood vessel endothelial cell migration; actin cytoskeleton organization; regulation of cell migration; angiogenesis;
	Sources:Amigo / QuickGO
Orthologs
	154810
	75723
	ENSG00000166025
	ENSMUSG00000013076
	Q8IY63
	Q9D4H4
	NM_001301007; NM_130847
	NM_001081395
	NP_001287936; NP_570899; NP_570899.1
	NP_001074864
	Wikidata
View/Edit Human	View/Edit Mouse

Angiomotin-like protein 1 is a protein that in humans is encoded by the AMOTL1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166025 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000013076 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nishimura M, Kakizaki M, Ono Y, Morimoto K, Takeuchi M, Inoue Y, Imai T, Takai Y (Feb 2002). "JEAP, a novel component of tight junctions in exocrine cells". J Biol Chem. 277 (7): 5583–7. doi:10.1074/jbc.M110154200. PMID 11733531.
^ "Entrez Gene: AMOTL1 angiomotin like 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166025 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000013076 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11733531-5] Nishimura M, Kakizaki M, Ono Y, Morimoto K, Takeuchi M, Inoue Y, Imai T, Takai Y (Feb 2002). "JEAP, a novel component of tight junctions in exocrine cells". J Biol Chem. 277 (7): 5583–7. doi:10.1074/jbc.M110154200. PMID 11733531.

[entrez-6] "Entrez Gene: AMOTL1 angiomotin like 1".

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