Anne Ferguson-Smith

Anne Ferguson-Smith
Colour portrait photograph of Anne Ferguson-Smith
Ferguson-Smith in 2017
Born
Anne Carla Ferguson-Smith

(1961-07-23) 23 July 1961 (age 63)
Baltimore, Maryland, U.S.
Alma mater
Spouse
Mark McHarg
(m. 1988)
Children2
FatherMalcolm Ferguson-Smith
Awards
Scientific career
Fields
InstitutionsUniversity of Cambridge
ThesisA genomic analysis of the human homeobox gene loci HOX 1 and HOX 2 (1989)
Doctoral advisorFrank Ruddle[1]
Other academic advisorsAzim Surani
Websitewww.ukri.org/people/anne-ferguson-smith/ Edit this at Wikidata

Anne Carla Ferguson-Smith CBE FRS FMedSci[2][3] (born 23 July 1961) is a mammalian developmental geneticist. She is the Arthur Balfour Professor of Genetics and Pro-Vice Chancellor for Research and International Partnerships at the University of Cambridge. Formerly head of the Department of Genetics at the University of Cambridge, she is a Fellow of Darwin College, Cambridge and serves as President of the Genetics Society.[4][5][6]

Ferguson-Smith is an authority on genomic imprinting and the epigenetic control of genome function in health and disease, and is recognised for her work on parental-origin effects and epigenetic mechanisms.[2] Her work has uncovered epigenetically regulated processes in development and over the life course, and identified key in vivo mechanisms involved in the maintenance of epigenetic states. She also explores communication between the environment and the genome with implications for health, disease and inheritance.[3]

  1. ^ Rabin, Mark; Hart, Charles P.; Ferguson-Smith, Anne; McGinnis, William; Levine, Michael; Ruddle, Frank H. (1985). "Two homoeo box loci mapped in evolutionarily related mouse and human chromosomes". Nature. 314 (6007): 175–178. Bibcode:1985Natur.314..175R. doi:10.1038/314175a0. ISSN 0028-0836. PMID 4038785. S2CID 4281111. Closed access icon
  2. ^ a b Anon (2017). "Professor Anne Ferguson-Smith FMedSci FRS". London: royalsociety.org. Archived from the original on 5 May 2017.
  3. ^ a b Anon (2012). "Professor Anne Ferguson-Smith FRS FMedSci". acmedsci.ac.uk. London: Academy of Medical Sciences. Archived from the original on 1 August 2016.
  4. ^ Nagano, T.; Mitchell, J. A.; Sanz, L. A.; Pauler, F. M.; Ferguson-Smith, A. C.; Feil, R.; Fraser, P. (2008). "The Air Noncoding RNA Epigenetically Silences Transcription by Targeting G9a to Chromatin". Science. 322 (5908): 1717–1720. Bibcode:2008Sci...322.1717N. doi:10.1126/science.1163802. ISSN 0036-8075. PMID 18988810. S2CID 35584331. Closed access icon
  5. ^ Witkowski, Jan (2016). "A Conversation with Anne Ferguson-Smith". Cold Spring Harbor Symposia on Quantitative Biology. 80: 321–323. doi:10.1101/sqb.2015.80.029983. ISSN 0091-7451. PMID 27325719.
  6. ^ Constância, Miguel; Hemberger, Myriam; Hughes, Jennifer; Dean, Wendy; Ferguson-Smith, Anne; Fundele, Reinald; Stewart, Francesca; Kelsey, Gavin; Fowden, Abigail; Sibley, Colin; Reik, Wolf (2002). "Placental-specific IGF-II is a major modulator of placental and fetal growth". Nature. 417 (6892): 945–948. doi:10.1038/nature00819. ISSN 0028-0836. PMID 12087403. S2CID 4421165. Closed access icon